Friday, April 3

The genetic mechanisms of mental illnesses are monitored using the model of the fruit industry

Graduated from Boazii University, Do. Dr. Arzu elik Fuss received his doctorate in 2002 from the University of Genetics. Fuss completed his research at New York University and began developing the nervous system in 2007 using the model organism of the fruit industry at Bondii University.

Fuss, TBTAK 1001-supporting scientific and technological research projects aim to reduce the genetic mechanisms of mental illness in humans by supporting the "Mental Disability (Id) Drosophila Models" from Boazii University.

The project, which will start at Boazii University and will last 30 months, is one of the first scientific studies in this field in Turkey.

In 2008 he was the owner of the Turkish Academy of Sciences Gen Bilim Human Language and the European Molecular Biology Organization. Dr. Arzu elik Fuss, who washed the AA reporter about his project, said he had done research on brain and eye development and on the perception of smells in animals and humans.

In this direction, Fuss explained that he used fruit kine as a model organism in his studies and explained that the development systems could be followed by comparing the information obtained with humans.

He explained that during his studies at Boazii University, he was interested in finding new mutations in a gene that is known to cause genetic diseases. After returning to Turkey after the gene disorders were known, he decided to take it in this area.

Fuss, who declared the gold on the funded project for intellectual disabilities on the causes of diseases but the causes of genetic disorders using the fruit industry model, continued:

"The rate of consanguineous marriages is as high in Iran as in Turkey. Many genes with intellectual disabilities have been discovered, but there is a wealth of information on how these genes can lead to disabilities. We are researching our research to address this gap to close and understand the mechanisms of the newly discovered genes in the patient. " At this point, we received support from the TBTAK 1001 program and focused on two genes found in fruit flies and began to take the mechanisms out of them. The research center also provides information support. Our doctoral students help us with our experiments. "


Do. Dr. Arzu Elik Fuss stated that Fragile X syndrome and Angelman syndrome exist among the psychological disease models that have so far been produced in the field of fruit cinema.

"The modeling is based on finding the fly gene that is homologous to the human disease gene. If we compare the human genome with the fly genome, we see that 75 percent of the disease genes are preserved. We now know a lot about the fruit fly set. The main reasons for the use of flies by model organisms is that their genome is sequenced, that the chromosome numbers are low, that they are fast, and that their maintenance is relatively simple and economical. With genes it is possible to mutate these genes, and with fruit flies you can mutating a particular cell or tissue with existing genetic approaches to do your research on the tissue you are interested in. It is also much more advanced to put the brain and nervous system into fruit cells. Business behavior offers many options for the wettest staining and test memory. For these reasons is t it is advantageous to use the model of the fruit industry in laboratories and especially in brain research. "


"We reject humanized transgenic fly water by adding mutations to the fly genome in our experiments." and characterize their cognitive skills. " he said.

Fuss expressed that the mentally retarded flies can still distinguish the smell due to the mutations generated and what smell they can remember with the electric arrow. and said they will determine.

Realizing that its goal is to contribute to the treatment of neurological and neurodegenerative diseases, Fuss has laid the foundation for understanding the mechanisms that make up the models and mental disability, but for the treatment of these and other neurological and neurodegenerative diseases Diseases contributed.

"We want to find drugs that improve the symptoms of the disease by performing chemical scans on the various disease models that we have and that we will repeat," said Fuss. We have submitted a project application to the Ministry of Development for two years under the horse, but the results are not yet clear. We hope we can start buying soon. "used expressions.

Source link

Leave a Reply

Your email address will not be published. Required fields are marked *